Human brain cell membranes are highly enriched with phosphatidylserine (PS). PS levels in these tissues ensure the membrane's fluidity and structure, thus their function. Nerve cells, in particular, depend on healthy membrane function for normal neurotransmitter metabolism and nerve signal transmission. Maintaining brain PS levels has been associated with normal and efficient signaling processes, efficient brain glucose consumption, and other biological pathways that are crucial to ensure normal and healthy cognitive and mental functions. Cognagen is a daily source of PS, as well as polyphenols from blueberry, which have been studied for their roles in brain health.